(Last updated : 2020-09-24 11:59:11)
  Motohiro Takeya
   Department   Kumamoto Health Science University  Department of Medical Technology, Faculty of Health Science
   Position  Professor
Basic Information
■ Research Fields
Experimental pathology, Respiratory medicine, Human pathology, Metabolism and endocrinology (Key Word:SR-AI, II(CD204),ACAT-1,CD204,LOX-1,CD36,LOX-1(Lectin-like oxidized LDL receptor-1),MCP-1,corosolic acid,SR-AI,II) 
Academic Achievements
■ Selected Publications
1. 2018/11 Article Development of Kupffer cell targeting type-I interferon for the treatment of hepatitis via inducing anti-inflammatory and immunomodulatory actions. Drug delivery pp.1067-1077 (Collaboration) 
2. 2018/07 Article Positive correlation between the density of macrophages and T-cells in undifferentiated sarcoma. Medical molecular morphology  (Collaboration) 
3. 2018/06 Article CD163 Is Required for Protumoral Activation of Macrophages in Human and Murine Sarcoma. Cancer research pp.3255-3266 (Collaboration) 
4. 2018/05 Article Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure. The Journal of investigative dermatology  (Collaboration) 
5. 2017/04 Article Cell adhesion molecule-1 (CADM1) expressed on adult T-cell leukemia/lymphoma cells is not involved in the interaction with macrophages. Journal of clinical and experimental hematopathology : JCEH pp.15-20 (Collaboration) 
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■ Grants
1. 2011~2013  Development of new therapeutic strategies for regulating macrophage activation by natural compounds  (Key Word : )
2. 2008~2010  Functional analysis of the ACAT-1-positive late endosomes in cholesterol-rich macrophages  (Key Word : )
3. 2008~2010  ROLE OF SCAVENGER RECEPTORS IN MACROPHAGE ACTIVATION AND THEIR APPLICATION FOR DIAGNOSIS AND THERAPY  (Key Word : )
4. 2007~2010  Academic project of oncogenic factors in malignant tumors and the related diseases in northeast China  (Key Word : )
5. 2005~2007  Identification and characterization of novel vesicular organelle appearing hyperlipidemic human macrophages  (Key Word : )
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