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ヒビノ イタル
HIBINO ITARU
日比野 至 所属 リハビリテーション学部 職種 教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2008/04 |
| 形態種別 | 研究論文（学術雑誌） |
| 標題 | Effect of Immobilization on Insoluble Collagen Concentration and Type I and Type III Collagen Isoforms of Rat Soleus Muscle |
| 執筆形態 | 共著 |
| 掲載誌名 | Journal of the Japanese Physical Therapy Association |
| 掲載区分 | 国内 |
| 巻・号・頁 | pp.1-6 |
| 著者・共著者 | Itaru Hibino, Minoru Okita, Takayuki Inoue, Yasuhiro Banno, Masahiro Hoso |
| 概要 | The purpose of this study was to clarify the mechanism governing muscle contracture in rat soleus muscle by identifying changes in ankle joint mobility, insoluble collagen concentration and type I and type III collagen isoforms following 1- and 3-week immobilizations. Insoluble collagen concentration in soleus muscles, which was unchanged after 1 week of immobilization, increased 3 weeks after immobilization. These results may be indicative of collagen fibers with strong intermolecular cross-links contained in the muscle was made increased relatively by 3 weeks of immobilization. On the other hand, the ratio of type III to type I collagen isoforms in muscular tissue increased following a 1-week immobilization; moreover, this ratio remained constant after 3 weeks of immobilization. These data suggested that muscle immobilization may induce type III collagen isoform expression. |