キムラ ケイサク   KIMURA KEISAKU
  木村 啓作
   所属   鍼灸学部 鍼灸学科
   職種   講師
言語種別 日本語
発行・発表の年月 2014
形態種別 研究論文
標題 Contributions of nitric oxide and prostaglandins to the local increase in muscle blood flow following manual acupuncture in rats.
執筆形態 その他
掲載誌名 Acupunct Med
著者・共著者 shinbara H, okubo M, Kimura K,mizunuma K, sumiya E
概要 The purpose of this study was to investigate the contributions of NO and PGs to the increase in MBF following MA. Male Sprague-Dawley rats were intraperitoneally injected with a non-selective NO synthase inhibitor, a non-selective cyclooxygenase inhibitor, a combination of L-NAME and indomethacin. We used the sparrow pecking acupuncture on the right tibialis anterior muscle. MA significantly increased MBF in the saline-injected group. This increase was significantly, but not completely, inhibited by L-NAME.Indomethacin did not suppress the increase. These results suggest that NO is a major factor in the MA-induced increase in MBF, whereas PGs dose not contribute to this increase. Moreover, non-NO and non-PG vasodilators appear to participate in this increase.
Epub ahead of print