TAKASHI Tanaka
Department Kumamoto Health Science University Division of Physical Therapy, Faculty of Health Science Position Assistant Professor |
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Date | 2018/11/04 |
Presentation Theme | MARCKSL1 in the amygdala controls the HPA axis and anxiety behaviors |
Conference | The 48th Annual Meeting of the Society for Neuroscience |
Promoters | Society for Neuroscience |
Conference Type | International |
Presentation Type | Poster |
Contribution Type | Collaborative |
Country | United States |
Venue | San Diego |
Holding period | 2018/11/03~2018/11/07 |
Publisher and common publisher | Tanaka T, Miyata S |
Details | Myristoylated alanine-rich C-kinase substrate like 1 (MARCKSL1) is a group of acidic proteins localized to the plasma membrane. Although MARCKSL1 is predominantly expressed in the immature brain, it remains localized in adult limbic regions associated with emotional processing. Our findings suggest that MARCKSL1 regulates amygdala circuitry to control the activity of the HPA axis, as well as induces anxiety-like behaviors in mice. |