TAKASHI Tanaka
   Department   Kumamoto Health Science University  Division of Physical Therapy, Faculty of Health Science
   Position   Assistant Professor
Date 2018/11/04
Presentation Theme MARCKSL1 in the amygdala controls the HPA axis and anxiety behaviors
Conference The 48th Annual Meeting of the Society for Neuroscience
Promoters Society for Neuroscience
Conference Type International
Presentation Type Poster
Contribution Type Collaborative
Country United States
Venue San Diego
Holding period 2018/11/03~2018/11/07
Publisher and common publisher Tanaka T, Miyata S
Details Myristoylated alanine-rich C-kinase substrate like 1 (MARCKSL1) is a group of acidic proteins localized to the plasma membrane. Although MARCKSL1 is predominantly expressed in the immature brain, it remains localized in adult limbic regions associated with emotional processing. Our findings suggest that MARCKSL1 regulates amygdala circuitry to control the activity of the HPA axis, as well as induces anxiety-like behaviors in mice.