ヒルタ オサム   Osamu HIRUTA
  蛭田 修
   所属   熊本保健科学大学  品質保証・精度管理学共同研究講座
   熊本保健科学大学大学院  保健科学研究科 保健科学専攻
   職位   特命教授
言語種別 英語
発行・発表の年月 1997/01
形態種別 研究論文 
査読 査読あり
標題 Application of Maxblend Fementor for Microbial Processes
執筆形態 共著
掲載誌名 Journal of fermentation and bioengineering
掲載区分国内
巻・号・頁 83(1),pp.79-86
総ページ数 8
著者・共著者 Osamu Hiruta, Kenji Yamamura, Hidehi Takebe, Takafumi Futamura, Katsuharu Iinuma, Hideo Tanaka
概要 Application of the Maxblend impeller to a bioreactor (MBF) was investigated. In comparison with turbine impeller fermentor (TBN). During the fermentative production of hyaluronic acid in TBN, the pH in some parts of the fermentor was lower than the optimum pH for hyaluronic acid production. On the other hand, when MBF was used, the pH distribution inside the fermentor was homogeneous throughout the cultivation, resulting to about 20% increase in the hyaluronic acid productivity compared with a TBN. In the case of γ-linolenic acid (GLA) production by Mortierella ramanniana, although the power consumption for liquid agitation was lower in the MBF equipped with a spiral sparger than in the TBN, small hard pellets were formed in former and this resulted in a higher GLA content of the lipid. This was because the shear stress distribution was more uniform inside the MBF than in the TBN under the same agitation conditions.