Yoshihiro Iwashita
   Department   Kumamoto Health Science University  Division of Physical Therapy, Faculty of Health Science
   Kumamoto Health Science University Graduate School  Division of Health Sciences, Graduate School of Health Sciences
   Position   Associate Professor
Language English
Publication Date 2015
Peer Review Peer reviewed
Title A possible reno-protective effect of systemic thermal stimulation in a mouse remnant kidney model
Contribution Type
Journal The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine
Journal TypeJapan
Volume, Issue, Page 78(2),pp.118-129
Author and coauthor Yoshihiro IWASHITA, Yoshiyasu YOZA, Hiroki KAMEYAMA, Masashi MUKOYAMA, Junich llYAMA, Kenichiro KITAMURA
Details The purpose of this experiment was to verify the safety of systemic low-temperature sauna treatment (ST) for the 5/6 remnant kidney mouse and to examine the effect of ST on urinary protein excretion. There are no clear adverse events associated with low-temperature sauna. Therefore, this study setting is safe in the CKD model mouse. Renal eNOS mRNA expression was increased by the low-temperature sauna. The present results suggest the possibility that ST might provide a renal protective effect by suppressing glomerular hypertension via stimulation of renal NO production in the CKD model mouse.