Yukinori kozuma
Department Kumamoto Health Science University Department of Medical Technology, Faculty of Health Science Kumamoto Health Science University Graduate School Division of Health Sciences, Graduate School of Health Sciences Position Associate Professor |
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Language | English |
Publication Date | 2019 |
Type | |
Peer Review | Peer reviewed |
Title | Stratifin inhibits SCFFBW7 formation and blocks ubiqutination of oncoproteins during the course of lung adenocartinogenesis. (査読付き) |
Contribution Type | |
Journal | Clin Cancer Res |
Journal Type | Another Country |
Volume, Issue, Page | 25,pp.2809-2820 |
Responsible for | 共同研究につき抽出不可能 |
Author and coauthor | Shiba-Ishi A, Hong J, Hirokawa T, Kim Y, Nakagawa T, Sakashita S, Sakamoto N, Kozuma Y, Sato Y, Noguchi M. |
Details | 肺腺癌において stratifin は過剰発現している。そこで、stratifin 阻害剤である Ticagrelor の効果について詳細に検討したところ、 Ticagrelor は新規肺腺癌治療薬として有望である可能性を見出した。 |