Yukinori kozuma
   Department   Kumamoto Health Science University  Department of Medical Technology, Faculty of Health Science
   Kumamoto Health Science University Graduate School  Division of Health Sciences, Graduate School of Health Sciences
   Position   Associate Professor
Language English
Publication Date 2019
Type
Peer Review Peer reviewed
Title Stratifin inhibits SCFFBW7 formation and blocks ubiqutination of oncoproteins during the course of lung adenocartinogenesis. (査読付き)
Contribution Type
Journal Clin Cancer Res
Journal TypeAnother Country
Volume, Issue, Page 25,pp.2809-2820
Responsible for 共同研究につき抽出不可能
Author and coauthor Shiba-Ishi A, Hong J, Hirokawa T, Kim Y, Nakagawa T, Sakashita S, Sakamoto N, Kozuma Y, Sato Y, Noguchi M.
Details 肺腺癌において stratifin は過剰発現している。そこで、stratifin 阻害剤である Ticagrelor の効果について詳細に検討したところ、 Ticagrelor は新規肺腺癌治療薬として有望である可能性を見出した。