TAKASHI Tanaka
Department Kumamoto Health Science University Division of Physical Therapy, Faculty of Health Science Kumamoto Health Science University Graduate School Division of Health Sciences, Graduate School of Health Sciences Position Associate Professor |
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Language | English |
Publication Date | 2018/04 |
Type | |
Peer Review | Peer reviewed |
Title | MARCKSL1 regulates spine formation in the amygdala and controls the hypothalamic-pituitary-adrenal axis and anxiety-like behaviors. |
Contribution Type | |
Journal | EBioMedicine |
Journal Type | Another Country |
Volume, Issue, Page | 30,pp.62-73 |
Authorship | Lead author,Corresponding author |
Author and coauthor | Tanaka T (corresponding author), Shimizu S, Ueno M, Fujihara Y, Ikawa M, Miyata S |
Details | マウスの扁桃体における細胞骨格制御因子MARCKSL1の増加が、神経スパインの数を制御することで視床下部の過活動依存的な不安症を誘発することを見出した。MARCKSL1が不安症の発症を制御できる治療の候補因子であることを明らかにした原著論文。 |
DOI | 10.1016/j.ebiom.2018.03.018 |
PMID | 29580842 |