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TAKASHI Tanaka
Department Kumamoto Health Science University Division of Physical Therapy, Faculty of Health Science Kumamoto Health Science University Graduate School Division of Health Sciences, Graduate School of Health Sciences Position Associate Professor |
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| Language | English |
| Publication Date | 2013/04 |
| Type | |
| Peer Review | Peer reviewed |
| Title | Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury |
| Contribution Type | |
| Journal | Cell Death & Disease |
| Journal Type | Another Country |
| Volume, Issue, Page | 4,pp.e567 |
| Authorship | Lead author |
| International coauthorship | International coauthorship |
| Author and coauthor | Tanaka T, Fujita Y, Ueno M, Shultz LD, Yamashita T |
| Details | 脳損傷モデルマウスの大脳皮質において、神経軸索の伸長阻害因子として報告されるSHP-1が増加・活性することを見出した。遺伝学的・薬理学的にSHP-1を抑制することで皮質脊髄路の神経発芽や運動機能回復が促進することを示した。 |
| DOI | 10.1038/cddis.2013.102 |
| PMID | 23559001 |