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ノムラ カヨ
Kayo NOMURA
野村 香代 所属 教育学部 職種 准教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2020/06/20 |
| 形態種別 | 研究論文 |
| 査読 | 査読あり |
| 標題 | Primitive reflexes in very low birth weight infants later diagnosed with autism spectrum disorder |
| 執筆形態 | 共著 |
| 掲載誌名 | Minerva Pediatrica |
| 掲載区分 | 国外 |
| 巻・号・頁 | Online ahead of print |
| 著者・共著者 | ◎Yukiyo NAGAI, Kayo NOMURA, Osamu UEMURA |
| 概要 | Of 88 very low birth weight infants (<1500g) born from April 2010 to March 2012, subjects comprised 38 examined for 18 primitive reflexes between age 38 and 45 wks corrected age and followed-up over 6 yrs. ASD was diagnosed using Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-5) and Autism Diagnostic Observation Schedule Second Edition (ADOS-2). We compared the number of abnormal primitive reflexes between two groups (11 children with and 19 without ASD) after excluding eight children with cerebral palsy in this case-control study.
The result suggests primitive reflexes can be one of the key elements in very early infancy to identify ASD in low birth weight infants. Abnormal hypoactive primitive reflex of low birth weight infants with ASD may inform future research of the pathogenesis of ASD. |