オヤマダ マサヒト   Oyamada Masahito
  小山田 正人
   所属   藤女子大学  人間生活学部 食物栄養学科
   職種   特任教授
言語種別 英語
発行・発表の年月 2006
形態種別 研究論文(学術雑誌)
査読 査読あり
標題 Different changes in the expression of multiple kinds of tight-junction proteins during ischemia-reperfusion injury of the rat ileum
執筆形態 共著
掲載誌名 ACTA HISTOCHEMICA ET CYTOCHEMICA
出版社・発行元 JAPAN SOC HISTOCHEMISTRY&CYTOCHEMISTRY
巻・号・頁 39(2),pp.35-45
著者・共著者 Kaori Inoue,Masahito Oyamada,Shoji Mitsufuji,Takeshi Okanoue,Tetsuro Takamatsu
概要 Dysfunction of tight junctions ( TJs), located at the most apical part of the intestinal epithelium, is believed to result in various complications in intestinal disease. However, the behaviors of multiple kinds of TJ proteins during ischemia-reperfusion injury are not understood in detail. To determine changes in expression and localization of TJ proteins during intestinal-barrier recovery, we induced intestinal ischemia-reperfusion injury in rats, measured mucosa-to-blood permeability of fluorescein isothiocyanate-dextran-4 kDa, and compared it with spatiotemporal changes of ZO-1, occludin, and claudin-1, -2, -3, -4, and -5 by immunoconfocal microscopy.
DOI 10.1267/ahc.05048
ISSN 00445991
PermalinkURL https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33646269016&origin=inward