オヤマダ マサヒト   Oyamada Masahito
  小山田 正人
   所属   藤女子大学  人間生活学部 食物栄養学科
   職種   特任教授
言語種別 英語
発行・発表の年月 2013
形態種別 研究論文(学術雑誌)
査読 査読あり
標題 Connexin expression and gap-junctional intercellular communication in ES cells and iPS cells
執筆形態 共著
掲載誌名 FRONTIERS IN PHARMACOLOGY
掲載区分国外
出版社・発行元 FRONTIERS RESEARCH FOUNDATION
巻・号・頁 4
担当区分 筆頭著者
著者・共著者 Masahito Oyamada,Kumiko Takebe,Aya Endo,Sachiko Hara,Yumiko Oyamada
概要 Pluripotent stem cells,i.e., embryonic stem (ES) and induced pluripotent stem (iPS) cells, can indefinitely proliferate without commitment and differentiate into all cell lineages. Many studies have demonstrated that mouse and human iPS cells are highly similar but not identical to their respective ES cell counterparts. The potential to generate basically any differentiated cell types from these cells offers the possibility to establish new models of mammalian development and to create new sources of cells for regenerative medicine. ES cells and iPS cells also provide useful models to study connexin expression and gap-junctional intercellular communication (GJIC) during cell differentiation and reprogramming. Because a substantial number of papers on these subjects have been published since our report, this Mini Review summarizes currently available data on connexin expression and GJIC in ES cells and iPS cells during undifferentiated
DOI 10.3389/fphar.2013.00085
ISSN 16639812
PermalinkURL https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84881576252&origin=inward